Ginkgo Biloba Extract

INCI: GINKGO BILOBA LEAF EXTRACT

CAS Number
90045-36-6
Function
Antioxidant; ginkgolides and flavonoids
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR Expert Panel (2024): Ginkgo Biloba Leaf Extract safe in current cosmetic practices when formulated to be non-sensitizing. Ginkgolic acid must stay below 5 ppm. Five leaf-derived ingredients confirmed safe; five others had insufficient data.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CAS 90045-36-6 (EC 289-896-4). EU: Not restricted under EC 1223/2009; permitted as skin conditioning agent and antioxidant. US: CIR reviewed 2024 - safe when formulated to be non-sensitizing; ginkgolic acid must be below 5 ppm.

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Concern Level: Low

Regulatory Flags

cir-reviewed no-sccs-opinion ginkgolic-acid-limit sensitization-conditional purity-dependent-safety

Frequently Asked Questions

Is Ginkgo Biloba Extract safe in cosmetics?

CAS 90045-36-6 (EC 289-896-4). EU: Not restricted under EC 1223/2009; permitted as skin conditioning agent and antioxidant. US: CIR reviewed 2024 - safe when formulated to be non-sensitizing; ginkgolic acid must be below 5 ppm. The EU classifies Ginkgo Biloba Extract as "permitted". Safety rating: GOOD.

Is Ginkgo Biloba Extract allowed in the EU?

Ginkgo Biloba Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginkgo Biloba Extract do in cosmetics?

Ginkgo Biloba Extract functions as: Antioxidant; ginkgolides and flavonoids. It is classified as a Antioxidant in our database. CAS number: 90045-36-6.

What is the Margin of Safety for Ginkgo Biloba Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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