Regulatory Status
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Safety Data
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Expert Verdict
Alkaloid concern: Glaucium flavum (Yellow Horned Poppy) contains isoquinoline alkaloids including glaucine, protopine, and sanguinarine; sanguinarine is cytotoxic and has been linked to oral leukoplakia; alkaloid content must be characterized and controlled; CPSR assessor will require compositional analysis, in vitro irritation, sensitization battery, and genotoxicity data
Regulatory Flags
Frequently Asked Questions
Is Glaucium flavum Leaf Extract safe in cosmetics?
Alkaloid concern: Glaucium flavum (Yellow Horned Poppy) contains isoquinoline alkaloids including glaucine, protopine, and sanguinarine; sanguinarine is cytotoxic and has been linked to oral leukoplakia; alkaloid content must be characterized and controlled; CPSR assessor will require compositional analysis, in vitro irritation, sensitization battery, and genotoxicity data The EU classifies Glaucium flavum Leaf Extract as "permitted". Safety rating: MODERATE.
Is Glaucium flavum Leaf Extract allowed in the EU?
Glaucium flavum Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glaucium flavum Leaf Extract do in cosmetics?
Glaucium flavum Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.
What is the Margin of Safety for Glaucium flavum Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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