Globularia Alypum Leaf Extract

INCI: GLOBULARIA ALYPUM LEAF EXTRACT

CAS Number
Not assigned (botanical extract)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted or prohibited under 21 CFR; no CIR final monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CIR review available. Traditional Mediterranean medicinal use suggests bioactivity requiring caution at higher concentrations; iridoid glycosides present may have pharmacological effects.

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Concern Level: Moderate

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Globularia Alypum Leaf Extract safe in cosmetics?

No CIR review available. Traditional Mediterranean medicinal use suggests bioactivity requiring caution at higher concentrations; iridoid glycosides present may have pharmacological effects. The EU classifies Globularia Alypum Leaf Extract as "permitted". Safety rating: MODERATE.

Is Globularia Alypum Leaf Extract allowed in the EU?

Globularia Alypum Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Globularia Alypum Leaf Extract do in cosmetics?

Globularia Alypum Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (botanical extract).

What is the Margin of Safety for Globularia Alypum Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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