Glucaric Acid

INCI: GLUCARIC ACID

CAS Number
87-73-0 (D-glucaric acid / D-saccharic acid)
Function
Chelating agent (related to glucarolactone via hydrolysis equilibrium)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR; no CIR monograph specific to glucaric acid

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Glucaric acid is the hydrolyzed form of glucarolactone. CIR assessed glucarolactone (2022) and concluded data insufficient โ€” impurities data and cosmetic-specific manufacturing data needed. Natural occurrence in cruciferous vegetables and fruits. No cosmetic-specific toxicology, HRIPT, or margin of safety data.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Glucaric Acid safe in cosmetics?

Glucaric acid is the hydrolyzed form of glucarolactone. CIR assessed glucarolactone (2022) and concluded data insufficient โ€” impurities data and cosmetic-specific manufacturing data needed. Natural occurrence in cruciferous vegetables and fruits. No cosmetic-specific toxicology, HRIPT, or margin of safety data. The EU classifies Glucaric Acid as "permitted". Safety rating: MODERATE.

Is Glucaric Acid allowed in the EU?

Glucaric Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glucaric Acid do in cosmetics?

Glucaric Acid functions as: Chelating agent (related to glucarolactone via hydrolysis equilibrium). It is classified as a cosmetic ingredient in our database. CAS number: 87-73-0 (D-glucaric acid / D-saccharic acid).

What is the Margin of Safety for Glucaric Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Glucaric Acid in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Glucaric Acid in your formulation.