Indole Acetic Acid

INCI: INDOLE ACETIC ACID

CAS Number
87-51-4 / FDA UNII: 6U1S09C61L
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited under 21 CFR; FDA UNII registered

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Plant hormone (auxin) with biological activity at low concentrations; light-sensitive with photodegradation risk; incompatible with strong oxidizers; moderate dermal penetration potential requires systemic exposure assessment for leave-on products.

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Indole Acetic Acid safe in cosmetics?

Plant hormone (auxin) with biological activity at low concentrations; light-sensitive with photodegradation risk; incompatible with strong oxidizers; moderate dermal penetration potential requires systemic exposure assessment for leave-on products. The EU classifies Indole Acetic Acid as "permitted". Safety rating: MODERATE.

Is Indole Acetic Acid allowed in the EU?

Indole Acetic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Indole Acetic Acid do in cosmetics?

Indole Acetic Acid functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 87-51-4 / FDA UNII: 6U1S09C61L.

What is the Margin of Safety for Indole Acetic Acid?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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