Glucosyl Ceramide

INCI: GLUCOSYL CERAMIDE

CAS Number
85187-36-4 (glycosphingolipid-class identifier)
Function
Skin conditioning agent, hair conditioning agent, barrier repair
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted โ€” CIR Expert Panel determined ceramides (including glucosyl ceramide) safe as used in cosmetics, with the caveat that bovine CNS-derived materials are prohibited per 21 CFR 700.27

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Source material matters โ€” bovine CNS tissue-derived ceramides are prohibited in the US (BSE risk). Plant-derived (phytosphingosine-based) sources are preferred and do not carry this risk.

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Glucosyl Ceramide safe in cosmetics?

Source material matters โ€” bovine CNS tissue-derived ceramides are prohibited in the US (BSE risk). Plant-derived (phytosphingosine-based) sources are preferred and do not carry this risk. The EU classifies Glucosyl Ceramide as "permitted". Safety rating: EXCELLENT.

Is Glucosyl Ceramide allowed in the EU?

Glucosyl Ceramide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glucosyl Ceramide do in cosmetics?

Glucosyl Ceramide functions as: Skin conditioning agent, hair conditioning agent, barrier repair. It is classified as a cosmetic ingredient in our database. CAS number: 85187-36-4 (glycosphingolipid-class identifier).

What is the Margin of Safety for Glucosyl Ceramide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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