Glutamoyl Aminoguanidine

INCI: GLUTAMOYL AMINOGUANIDINE

CAS Number
Not publicly established in major databases
Function
Emollient / skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not specifically restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major data gap. Aminoguanidine is a known carbonyl scavenger and AGE inhibitor but has systemic toxicity concerns at oral doses. Dermal safety profile for the conjugate is unpublished. CPSR assessor would require acute dermal toxicity, sensitization (DPRA/KeratinoSens), and irritation data before sign-off.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Glutamoyl Aminoguanidine safe in cosmetics?

Major data gap. Aminoguanidine is a known carbonyl scavenger and AGE inhibitor but has systemic toxicity concerns at oral doses. Dermal safety profile for the conjugate is unpublished. CPSR assessor would require acute dermal toxicity, sensitization (DPRA/KeratinoSens), and irritation data before sign-off. The EU classifies Glutamoyl Aminoguanidine as "permitted". Safety rating: MODERATE.

Is Glutamoyl Aminoguanidine allowed in the EU?

Glutamoyl Aminoguanidine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glutamoyl Aminoguanidine do in cosmetics?

Glutamoyl Aminoguanidine functions as: Emollient / skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly established in major databases.

What is the Margin of Safety for Glutamoyl Aminoguanidine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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