Is Glycyrrhetinyl Stearate safe in cosmetics?
Glycyrrhetinyl Stearate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Glycyrrhetinyl Stearate
Also known as: UNII-R63V8Q8M4R, 3-Stearoyloxy glycyrrhetinic acid, Olean-12-en-29-oic acid, 11-oxo-3-((1-oxooctadecyl)oxy)-, (3beta,20beta)-, Olean-12-en-30-oic acid, 3beta-hydroxy-11-oxo-, stearate, Stearic acid, ester with 3beta-hydroxy-11-oxoolean-12-en-30-oic acid
INCI: GLYCYRRHETINYL STEARATE
Glycyrrhetinyl Stearate (CAS 4827-59-2) is a cosmetic cosmetic ingredient functioning as Humectant, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 4827-59-2 →
Auto-generated CPSR Part A draft with source citations
Function
Humectant, skin conditioning
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-2,4a,6a,6b,9,9,12a-heptamethyl-10-octadecanoyloxy-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
InChIKey
NZGKLLOWEPXNDG-SSCMEWPNSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR restriction; covered under CIR assessment of Glycyrrhetinic Acid and its esters as safe
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glycyrrhetinyl Stearate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Glycyrrhetinyl Stearate.
Known Synonyms
UNII-R63V8Q8M4R
3-Stearoyloxy glycyrrhetinic acid
Olean-12-en-29-oic acid, 11-oxo-3-((1-oxooctadecyl)oxy)-, (3beta,20beta)-
Olean-12-en-30-oic acid, 3beta-hydroxy-11-oxo-, stearate
Stearic acid, ester with 3beta-hydroxy-11-oxoolean-12-en-30-oic acid
Chemical Function
Humectant
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Frequently Asked Questions
Is Glycyrrhetinyl Stearate allowed in the EU?
Glycyrrhetinyl Stearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycyrrhetinyl Stearate do in cosmetics?
Glycyrrhetinyl Stearate functions as: Humectant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 4827-59-2.
Compliance Tools
Check Glycyrrhetinyl Stearate compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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