Is Guaiacol Acetate safe in cosmetics?
Guaiacol Acetate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Guaiacol Acetate
INCI: GUAIACOL ACETATE
Guaiacol Acetate (CAS 613-70-7) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 613-70-7 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2-methoxyphenyl) acetate
InChIKey
BHJHPYFAYGAPLS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA GRAS 3687; no cosmetic-specific CFR restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Guaiacol Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (6)
JECFA Number
718
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
1-ACETOXY-2-METHOXYBENZENE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/44 | FAS 46-JECFA 55/165
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
GUAIACYL ACETATE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/44 | FAS 46-JECFA 55/165
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
o-ACETOXYANISOLE | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/44 | FAS 46-JECFA 55/165
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ACETYL GUAIACOL | 2000 | No safety concern at current levels of intake when used as a flavouring agent | TRS 901-JECFA 55/44 | FAS 46-JECFA 55/165
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Guaiacol Acetate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Guaiacol Acetate allowed in the EU?
Guaiacol Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Guaiacol Acetate do in cosmetics?
Guaiacol Acetate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 613-70-7.
Is Guaiacol Acetate used outside cosmetics?
Guaiacol Acetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Guaiacol Acetate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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