Guaiacol Acetate

INCI: GUAIACOL ACETATE

CAS Number
613-70-7
Function
Fragrance ingredient
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS 3687; no cosmetic-specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS hazards H315, H319, H335 indicate skin, eye, and respiratory irritant potential. Limited standalone toxicological data available; safety profile dependent on parent compound assessment as hydrolysis yields guaiacol and acetic acid.

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Guaiacol Acetate safe in cosmetics?

GHS hazards H315, H319, H335 indicate skin, eye, and respiratory irritant potential. Limited standalone toxicological data available; safety profile dependent on parent compound assessment as hydrolysis yields guaiacol and acetic acid. The EU classifies Guaiacol Acetate as "permitted". Safety rating: MODERATE.

Is Guaiacol Acetate allowed in the EU?

Guaiacol Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Guaiacol Acetate do in cosmetics?

Guaiacol Acetate functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 613-70-7.

What is the Margin of Safety for Guaiacol Acetate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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