Guanidine Carbonate

INCI: GUANIDINE CARBONATE

CAS Number
593-85-1
Function
Buffering agent, pH adjuster; used in no-lye hair relaxer systems
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR Parts 700โ€“740

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS H302 (harmful if swallowed), H315 (skin irritation), H318/H319 (serious eye damage/irritation), H335 (respiratory irritation). High-pH formulations (โ‰ฅ12) cause chemical burns if misused. Scalp contact time must be controlled.

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Concern Level: Moderate

Frequently Asked Questions

Is Guanidine Carbonate safe in cosmetics?

GHS H302 (harmful if swallowed), H315 (skin irritation), H318/H319 (serious eye damage/irritation), H335 (respiratory irritation). High-pH formulations (โ‰ฅ12) cause chemical burns if misused. Scalp contact time must be controlled. The EU classifies Guanidine Carbonate as "permitted". Safety rating: MODERATE.

Is Guanidine Carbonate allowed in the EU?

Guanidine Carbonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Guanidine Carbonate do in cosmetics?

Guanidine Carbonate functions as: Buffering agent, pH adjuster; used in no-lye hair relaxer systems. It is classified as a cosmetic ingredient in our database. CAS number: 593-85-1.

What is the Margin of Safety for Guanidine Carbonate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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