Harpagophytum Extract (Devil's Claw)
INCI: HARPAGOPHYTUM PROCUMBENS ROOT EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
Active iridoid glycosides (harpagoside, harpagide, procumbide) primarily studied for oral anti-inflammatory use; limited topical toxicology data; potential drug interactions if systemically absorbed including anticoagulants and antidiabetics.
Regulatory Flags
Frequently Asked Questions
Is Harpagophytum Extract (Devil's Claw) safe in cosmetics?
Active iridoid glycosides (harpagoside, harpagide, procumbide) primarily studied for oral anti-inflammatory use; limited topical toxicology data; potential drug interactions if systemically absorbed including anticoagulants and antidiabetics. The EU classifies Harpagophytum Extract (Devil's Claw) as "permitted". Safety rating: GOOD.
Is Harpagophytum Extract (Devil's Claw) allowed in the EU?
Harpagophytum Extract (Devil's Claw) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Harpagophytum Extract (Devil's Claw) do in cosmetics?
Harpagophytum Extract (Devil's Claw) functions as: Skin conditioning, soothing (anti-inflammatory). It is classified as a cosmetic ingredient in our database. CAS number: 84988-65-8.
What is the Margin of Safety for Harpagophytum Extract (Devil's Claw)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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