Lawsonia Inermis Callus Culture Extract

INCI: LAWSONIA INERMIS CALLUS CULTURE EXTRACT

CAS Number
84988-66-9
Function
Skin conditioning, hair conditioning, hair dyeing, antimicrobial, antioxidant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed for cosmetic use; FDA permits henna only for hair dyeing, not for direct skin application (e.g., temporary tattoos are considered misbranded/adulterated).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains lawsone as a natural constituent - genotoxicity concerns apply. The callus culture origin may result in different lawsone concentrations compared to whole-plant extracts. PPD (para-phenylenediamine) contamination risk in commercial "black henna" products. Biotechnology-derived version of henna; callus culture method may allow controlled composition versus wild-harvested plant material

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Lawsonia Inermis Callus Culture Extract safe in cosmetics?

Contains lawsone as a natural constituent - genotoxicity concerns apply. The callus culture origin may result in different lawsone concentrations compared to whole-plant extracts. PPD (para-phenylenediamine) contamination risk in commercial "black henna" products. Biotechnology-derived version of henna; callus culture method may allow controlled composition versus wild-harvested plant material The EU classifies Lawsonia Inermis Callus Culture Extract as "permitted". Safety rating: MODERATE.

Is Lawsonia Inermis Callus Culture Extract allowed in the EU?

Lawsonia Inermis Callus Culture Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lawsonia Inermis Callus Culture Extract do in cosmetics?

Lawsonia Inermis Callus Culture Extract functions as: Skin conditioning, hair conditioning, hair dyeing, antimicrobial, antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84988-66-9.

What is the Margin of Safety for Lawsonia Inermis Callus Culture Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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