Lawsonia Alba Leaf Extract

INCI: LAWSONIA INERMIS LEAF EXTRACT

CAS Number
84988-39-0 (Lawsonia Inermis extract); active Lawsone: 83-72-7
Function
Hair Dyeing, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes FDA approves henna (Lawsonia Inermis) only as a hair dye (21 CFR 73.2190); not approved for skin application (mehndi/body art use is non-compliant).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Lawsone demonstrates in vitro clastogenic and mutagenic activity with unexcluded genotoxic potential; FDA restricts to hair dye applications only; risk of PPD contamination and skin-use non-compliance.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Lawsonia Alba Leaf Extract safe in cosmetics?

Lawsone demonstrates in vitro clastogenic and mutagenic activity with unexcluded genotoxic potential; FDA restricts to hair dye applications only; risk of PPD contamination and skin-use non-compliance. The EU classifies Lawsonia Alba Leaf Extract as "restricted". Safety rating: MODERATE.

Is Lawsonia Alba Leaf Extract allowed in the EU?

Lawsonia Alba Leaf Extract EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lawsonia Alba Leaf Extract do in cosmetics?

Lawsonia Alba Leaf Extract functions as: Hair Dyeing, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84988-39-0 (Lawsonia Inermis extract); active Lawsone: 83-72-7.

What is the Margin of Safety for Lawsonia Alba Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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