Moderate Cosmetic Ingredient

HC Orange No. 6

INCI: HC ORANGE NO. 6

CAS Number
1449653-83-1
Function
Hair dyeing (direct/semi-permanent dye)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. 0.5%
🇺🇸 US Status permitted
US Notes Falls under the coal tar hair dye exemption (FD\&C Act §601(a)); permitted with appropriate caution labeling and patch test instructions; not subject to batch certification

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

SCCS evaluated toxicological profile including acute toxicity, skin sensitization, mutagenicity/genotoxicity data; restricted concentration reflects safety margins. Nitro dye class; provides orange shades in non-oxidative systems; diffuses into hair cortex without requiring a developer

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is HC Orange No. 6 safe in cosmetics?

SCCS evaluated toxicological profile including acute toxicity, skin sensitization, mutagenicity/genotoxicity data; restricted concentration reflects safety margins. Nitro dye class; provides orange shades in non-oxidative systems; diffuses into hair cortex without requiring a developer The EU classifies HC Orange No. 6 as "restricted". Safety rating: MODERATE.

Is HC Orange No. 6 allowed in the EU?

HC Orange No. 6 EU regulatory status: restricted. Maximum allowed concentration: 0.5%. This is based on EU Regulation 1223/2009 and its amendments.

What does HC Orange No. 6 do in cosmetics?

HC Orange No. 6 functions as: Hair dyeing (direct/semi-permanent dye). It is classified as a cosmetic ingredient in our database. CAS number: 1449653-83-1.

What is the Margin of Safety for HC Orange No. 6?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check HC Orange No. 6 compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Solvent Red 3
Moderate
Arrabidaea Chica Leaf/Stem Extract
Moderate
HC Yellow No. 6
Poor
Sodium Sulfanilate
Moderate
4-Amino-2-Nitrophenol ⚠️
Poor
Browse all 30,000+ ingredients →
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