HEMA Acetoacetate

INCI: HEMA ACETOACETATE

CAS Number
21282-97-3
Function
Film forming (nail enhancement)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted - CIR concluded safe as used in nail enhancement products when labeled to avoid skin contact

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR restricts use to nail enhancement only; SCCS identified HEMA class as weak-to-moderate sensitizers; cross-reactivity risk with other methacrylates; must label avoid skin contact

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is HEMA Acetoacetate safe in cosmetics?

CIR restricts use to nail enhancement only; SCCS identified HEMA class as weak-to-moderate sensitizers; cross-reactivity risk with other methacrylates; must label avoid skin contact The EU classifies HEMA Acetoacetate as "restricted". Safety rating: MODERATE.

Is HEMA Acetoacetate allowed in the EU?

HEMA Acetoacetate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does HEMA Acetoacetate do in cosmetics?

HEMA Acetoacetate functions as: Film forming (nail enhancement). It is classified as a cosmetic ingredient in our database. CAS number: 21282-97-3.

What is the Margin of Safety for HEMA Acetoacetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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