Regulatory Status
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Safety Data
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Expert Verdict
Typically sourced from Aspergillus niger fermentation; assess for residual microbial proteins. Enzyme preparations are hygroscopic with occupational inhalation sensitization risk during manufacturing. Limited cosmetic-specific toxicological dossier.
Regulatory Flags
Frequently Asked Questions
Is Hesperidinase safe in cosmetics?
Typically sourced from Aspergillus niger fermentation; assess for residual microbial proteins. Enzyme preparations are hygroscopic with occupational inhalation sensitization risk during manufacturing. Limited cosmetic-specific toxicological dossier. The EU classifies Hesperidinase as "permitted". Safety rating: MODERATE.
Is Hesperidinase allowed in the EU?
Hesperidinase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hesperidinase do in cosmetics?
Hesperidinase functions as: Skin conditioning (enzyme); hydrolyzes hesperidin glycosidic bonds. It is classified as a cosmetic ingredient in our database. CAS number: 37213-47-1.
What is the Margin of Safety for Hesperidinase?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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