Hexadecenoic Acid

INCI: HEXADECENOIC ACID

CAS Number
373-49-9 (cis-9-hexadecenoic / palmitoleic acid); other positional isomers exist (e.g., 2091-29-4)
Function
Emollient, skin-conditioning agent, surfactant, cleansing
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; naturally occurring fatty acid

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Naturally occurring fatty acid with no significant safety concerns; verify isomer identity as positional isomers affect CAS assignment and properties. Store under nitrogen or with antioxidant protection due to susceptibility to auto-oxidation.

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Concern Level: Low

Frequently Asked Questions

Is Hexadecenoic Acid safe in cosmetics?

Naturally occurring fatty acid with no significant safety concerns; verify isomer identity as positional isomers affect CAS assignment and properties. Store under nitrogen or with antioxidant protection due to susceptibility to auto-oxidation. The EU classifies Hexadecenoic Acid as "permitted". Safety rating: EXCELLENT.

Is Hexadecenoic Acid allowed in the EU?

Hexadecenoic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexadecenoic Acid do in cosmetics?

Hexadecenoic Acid functions as: Emollient, skin-conditioning agent, surfactant, cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 373-49-9 (cis-9-hexadecenoic / palmitoleic acid); other positional isomers exist (e.g., 2091-29-4).

What is the Margin of Safety for Hexadecenoic Acid?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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