Hexadienyl Isobutyrate

INCI: 2,4-HEXADIENYL ISOBUTYRATE

CAS Number
16491-24-0
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Conjugated diene system theoretically susceptible to oxidation; RIFM evaluated genotoxicity, repeated dose, reproductive toxicity, local respiratory, and phototoxicity โ€” all cleared.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Hexadienyl Isobutyrate safe in cosmetics?

Conjugated diene system theoretically susceptible to oxidation; RIFM evaluated genotoxicity, repeated dose, reproductive toxicity, local respiratory, and phototoxicity โ€” all cleared. The EU classifies Hexadienyl Isobutyrate as "permitted". Safety rating: GOOD.

Is Hexadienyl Isobutyrate allowed in the EU?

Hexadienyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexadienyl Isobutyrate do in cosmetics?

Hexadienyl Isobutyrate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 16491-24-0.

What is the Margin of Safety for Hexadienyl Isobutyrate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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