Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene)

INCI: HEXAHYDRO-TETRAMETHYL-SPIRODIOXOLANE-METHANONAPHTHALENE

CAS Number
154171-77-4
Function
Fragrance / Perfuming
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific restriction under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Newer synthetic fragrance ingredient with limited published safety data; RIFM monograph or supplier toxicological documentation recommended for cosmetic product safety report support.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) safe in cosmetics?

Newer synthetic fragrance ingredient with limited published safety data; RIFM monograph or supplier toxicological documentation recommended for cosmetic product safety report support. The EU classifies Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) as "prohibited". Safety rating: MODERATE.

Is Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) allowed in the EU?

Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) do in cosmetics?

Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 154171-77-4.

What is the Margin of Safety for Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hexahydro-tetramethyl-spirodioxolane-methanonaphthalene (Spirambrene) in your formulation.