Is Hexapeptide-11 safe in cosmetics?
Hexapeptide-11 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Hexapeptide-11
INCI: HEXAPEPTIDE-11
Hexapeptide-11 (CAS Not publicly assigned) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS Not publicly assigned →
Function
Skin Conditioning
Editorial assessment
MODERATE
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR prohibition
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexapeptide-11.
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Hexapeptide-11, relevant to systemic exposure and MoS calculations.
Absorption %
1-3%
Penetration Level
surface
Penetration Depth
stratum corneum
Molecular Weight
673.8 Da
Log P
-0.8
Systemic Absorption
minimal
Topical Bioavailability
0.5-2%
Safety Margin Factor
minimal
Vehicle Dependent
Yes — absorption varies by formulation
Source: Cosmetic Science
Editorial summary
Preliminary editorial summary for Hexapeptide-11 — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Hexapeptide-11 allowed in the EU?
Hexapeptide-11 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-11 do in cosmetics?
Hexapeptide-11 functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned.
Compliance Tools
Check Hexapeptide-11 compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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