Hexapeptide-23

INCI: HEXAPEPTIDE-23

CAS Number
Not publicly assigned for the bare peptide form
Function
Skin Conditioning; the acylated derivative (Myristoyl Hexapeptide-23) also has antimicrobial properties
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically prohibited or restricted; generally allowed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No completed CIR safety review for the bare peptide; the myristoyl derivative (SpecPed MH23P) has been marketed as having broad-spectrum antibacterial properties effective against acne. Synthetic hexapeptide; when acylated with myristic acid, gains antimicrobial activity and acne-inhibiting function; bare form primarily functions as a skin conditioner

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Concern Level: Moderate

Frequently Asked Questions

Is Hexapeptide-23 safe in cosmetics?

No completed CIR safety review for the bare peptide; the myristoyl derivative (SpecPed MH23P) has been marketed as having broad-spectrum antibacterial properties effective against acne. Synthetic hexapeptide; when acylated with myristic acid, gains antimicrobial activity and acne-inhibiting function; bare form primarily functions as a skin conditioner The EU classifies Hexapeptide-23 as "permitted". Safety rating: MODERATE.

Is Hexapeptide-23 allowed in the EU?

Hexapeptide-23 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexapeptide-23 do in cosmetics?

Hexapeptide-23 functions as: Skin Conditioning; the acylated derivative (Myristoyl Hexapeptide-23) also has antimicrobial properties. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned for the bare peptide form.

What is the Margin of Safety for Hexapeptide-23?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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