Regulatory Status
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Safety Data
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Expert Verdict
Hexapeptide-3 is a fibronectin-mimetic peptide permitted in cosmetics; distinguish from Acetyl Hexapeptide-3 (Argireline). No CIR or SCCS review; molecular weight >500 Da supports low systemic absorption.
Frequently Asked Questions
Is Hexapeptide-3 safe in cosmetics?
Hexapeptide-3 is a fibronectin-mimetic peptide permitted in cosmetics; distinguish from Acetyl Hexapeptide-3 (Argireline). No CIR or SCCS review; molecular weight >500 Da supports low systemic absorption. The EU classifies Hexapeptide-3 as "permitted". Safety rating: MODERATE.
Is Hexapeptide-3 allowed in the EU?
Hexapeptide-3 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-3 do in cosmetics?
Hexapeptide-3 functions as: Skin conditioning — fibronectin-mimetic peptide (sequence: Ala-Asp-Leu-Lys-Pro-Thr); promotes ECM protein synthesis and cell adhesion. It is classified as a cosmetic ingredient in our database. CAS number: 1205679-02-2.
What is the Margin of Safety for Hexapeptide-3?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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