Hexapeptide-42

INCI: HEXAPEPTIDE-42

CAS Number
Not publicly available
Function
Not yet specified in COSMILE Europe; synthetic origin confirmed
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed as prohibited/restricted in 21 CFR; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Function not formally assigned in CosIng with extremely limited public data; CPSR assessor will likely require full toxicological justification or read-across.

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Concern Level: High

Frequently Asked Questions

Is Hexapeptide-42 safe in cosmetics?

Function not formally assigned in CosIng with extremely limited public data; CPSR assessor will likely require full toxicological justification or read-across. The EU classifies Hexapeptide-42 as "permitted". Safety rating: POOR.

Is Hexapeptide-42 allowed in the EU?

Hexapeptide-42 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexapeptide-42 do in cosmetics?

Hexapeptide-42 functions as: Not yet specified in COSMILE Europe; synthetic origin confirmed. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly available.

What is the Margin of Safety for Hexapeptide-42?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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