Hexetidine

INCI: HEXETIDINE

CAS Number
| Hexenyloxy-propanenitrile
Function
Antimicrobial, oral care, preservative
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in OTC oral care products; not specifically restricted under 21 CFR for cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hexetidine is a permitted antimicrobial preservative approved for use in oral care products in both the EU and US with established adequate margin of safety.

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Concern Level: Moderate

Regulatory Flags

preservative eu_cosing_listed

Frequently Asked Questions

Is Hexetidine safe in cosmetics?

Hexetidine is a permitted antimicrobial preservative approved for use in oral care products in both the EU and US with established adequate margin of safety. The EU classifies Hexetidine as "permitted". Safety rating: MODERATE.

Is Hexetidine allowed in the EU?

Hexetidine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexetidine do in cosmetics?

Hexetidine functions as: Antimicrobial, oral care, preservative. It is classified as a cosmetic ingredient in our database. CAS number: | Hexenyloxy-propanenitrile.

What is the Margin of Safety for Hexetidine?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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