Hexyl Aminolevulinate HCl

INCI: HEXYL AMINOLEVULINATE HCL

CAS Number
140898-91-5
Function
Photosensitizer precursor; pharmaceutical active ingredient
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA-approved drug (Cysview) for bladder cancer detection; not a recognized cosmetic ingredient under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Induces protoporphyrin IX production causing severe phototoxicity upon light exposure; designed for cellular apoptosis in tumor tissue under specific wavelengths; contraindicated for leave-on cosmetic formulations; incidental light exposure post-application could cause burns, erythema, or photodamage.

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Concern Level: High

Frequently Asked Questions

Is Hexyl Aminolevulinate HCl safe in cosmetics?

Induces protoporphyrin IX production causing severe phototoxicity upon light exposure; designed for cellular apoptosis in tumor tissue under specific wavelengths; contraindicated for leave-on cosmetic formulations; incidental light exposure post-application could cause burns, erythema, or photodamage. The EU classifies Hexyl Aminolevulinate HCl as "restricted". Safety rating: POOR.

Is Hexyl Aminolevulinate HCl allowed in the EU?

Hexyl Aminolevulinate HCl EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexyl Aminolevulinate HCl do in cosmetics?

Hexyl Aminolevulinate HCl functions as: Photosensitizer precursor; pharmaceutical active ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 140898-91-5.

What is the Margin of Safety for Hexyl Aminolevulinate HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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