Hexyl Nicotinate

INCI: HEXYL NICOTINATE

CAS Number
23597-82-2
Function
Skin conditioning agent (rubefacient/vasodilator); used in sun-tanning, slimming, and warming products
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no 21 CFR 700 restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Skin irritant (H315); serious eye irritant (H319); respiratory irritant (H335); vasodilatory mechanism of action inherently increases blood flow and may enhance co-penetration of other actives; limited published cosmetic-specific toxicological data

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Concern Level: High

Frequently Asked Questions

Is Hexyl Nicotinate safe in cosmetics?

Skin irritant (H315); serious eye irritant (H319); respiratory irritant (H335); vasodilatory mechanism of action inherently increases blood flow and may enhance co-penetration of other actives; limited published cosmetic-specific toxicological data The EU classifies Hexyl Nicotinate as "permitted". Safety rating: MODERATE.

Is Hexyl Nicotinate allowed in the EU?

Hexyl Nicotinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexyl Nicotinate do in cosmetics?

Hexyl Nicotinate functions as: Skin conditioning agent (rubefacient/vasodilator); used in sun-tanning, slimming, and warming products. It is classified as a cosmetic ingredient in our database. CAS number: 23597-82-2.

What is the Margin of Safety for Hexyl Nicotinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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