Hibiscolide

INCI: HIBISCOLIDE

CAS Number
6707-60-4 (12-Oxahexadecanolide)
Function
Fragrance ingredient — macrocyclic musk (oriental/musk family)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not specifically restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Must comply with IFRA Standards for maximum use levels by product category; environmental persistence is a concern for macrocyclic musks; requires IFRA certificate for CPSR

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Concern Level: Moderate

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Hibiscolide safe in cosmetics?

Must comply with IFRA Standards for maximum use levels by product category; environmental persistence is a concern for macrocyclic musks; requires IFRA certificate for CPSR The EU classifies Hibiscolide as "permitted". Safety rating: MODERATE.

Is Hibiscolide allowed in the EU?

Hibiscolide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hibiscolide do in cosmetics?

Hibiscolide functions as: Fragrance ingredient — macrocyclic musk (oriental/musk family). It is classified as a cosmetic ingredient in our database. CAS number: 6707-60-4 (12-Oxahexadecanolide).

What is the Margin of Safety for Hibiscolide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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