Hydrangea macrophylla Extract

INCI: HYDRANGEA MACROPHYLLA EXTRACT

CAS Number
97722-03-7
Function
Fragrance, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydrangea macrophylla extract contains hydrangenol with demonstrated estrogenic activity in vitro and potential cyanogenic compounds; cosmetic safety opinion unavailable and extraction solvent standardization must be documented.

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

plant-extract fragrance-component natural-origin

Frequently Asked Questions

Is Hydrangea macrophylla Extract safe in cosmetics?

Hydrangea macrophylla extract contains hydrangenol with demonstrated estrogenic activity in vitro and potential cyanogenic compounds; cosmetic safety opinion unavailable and extraction solvent standardization must be documented. The EU classifies Hydrangea macrophylla Extract as "permitted". Safety rating: MODERATE.

Is Hydrangea macrophylla Extract allowed in the EU?

Hydrangea macrophylla Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrangea macrophylla Extract do in cosmetics?

Hydrangea macrophylla Extract functions as: Fragrance, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 97722-03-7.

What is the Margin of Safety for Hydrangea macrophylla Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Hydrangea macrophylla Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hydrangea macrophylla Extract in your formulation.