Hydratropic Aldehyde (2-Phenylpropanal)
INCI: HYDRATROPIC ALDEHYDE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Hydratropic Aldehyde (2-Phenylpropanal). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 10 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
| NOAEL | 10 mg/kg bw/day | oral | rat | Short Term Toxicity | COSMOS_DB |
Expert Verdict
GHS: H315 skin irritation, H319 serious eye irritation, H335 respiratory irritation. EU Annex III fragrance allergen with mandatory label declaration. IFRA restricts maximum use levels by product category. Not listed as carcinogen (NTP, IARC, OSHA). CPSR must include quantified level and IFRA certificate.
Regulatory Flags
Frequently Asked Questions
Is Hydratropic Aldehyde (2-Phenylpropanal) safe in cosmetics?
GHS: H315 skin irritation, H319 serious eye irritation, H335 respiratory irritation. EU Annex III fragrance allergen with mandatory label declaration. IFRA restricts maximum use levels by product category. Not listed as carcinogen (NTP, IARC, OSHA). CPSR must include quantified level and IFRA certificate. The EU classifies Hydratropic Aldehyde (2-Phenylpropanal) as "restricted". Safety rating: MODERATE. 3 toxicological study endpoint(s) are available in our database.
Is Hydratropic Aldehyde (2-Phenylpropanal) allowed in the EU?
Hydratropic Aldehyde (2-Phenylpropanal) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydratropic Aldehyde (2-Phenylpropanal) do in cosmetics?
Hydratropic Aldehyde (2-Phenylpropanal) functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 93-53-8.
What is the Margin of Safety for Hydratropic Aldehyde (2-Phenylpropanal)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydratropic Aldehyde (2-Phenylpropanal)?
The NOAEL (No Observed Adverse Effect Level) for Hydratropic Aldehyde (2-Phenylpropanal) is 500 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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