Is Hydrocortisone Acetate safe in cosmetics?
Hydrocortisone Acetate has a safety rating of "POOR" in our database. EU status: prohibited. US status: restricted.
POOR
Cosmetic Ingredient
Hydrocortisone Acetate
INCI: HYDROCORTISONE ACETATE
Hydrocortisone Acetate (CAS 50-03-3 (EC\# 200-004-4)) is a cosmetic cosmetic ingredient functioning as Anti-inflammatory glucocorticoid. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 50-03-3 (EC\# 200-004-4) →
Function
Anti-inflammatory glucocorticoid
Editorial assessment
POOR
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
prohibited
US US Status
restricted
US Notes
Classified as OTC drug active (21 CFR 348); inclusion in a cosmetic renders the product a drug under the FDCA. Not permitted as a cosmetic-only ingredient.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hydrocortisone Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Hydrocortisone Acetate — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Hydrocortisone Acetate allowed in the EU?
Hydrocortisone Acetate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrocortisone Acetate do in cosmetics?
Hydrocortisone Acetate functions as: Anti-inflammatory glucocorticoid. It is classified as a cosmetic ingredient in our database. CAS number: 50-03-3 (EC\# 200-004-4).
Compliance Tools
Check Hydrocortisone Acetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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