Good Surfactant NOAEL Data

Hydrogenated Castor Oil Research

INCI: HYDROGENATED CASTOR OIL

CAS Number
8001-78-3
Function
Surfactant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 30%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Indirect food additive (21 CFR 175-178); parent oil GRAS for laxative

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

10 study endpoints found for Hydrogenated Castor Oil Research. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 10 other oral rat oral REACH
NOAEL >=1333 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 15 other oral dog oral REACH
NOAEL 200000 mg/kg bw/day oral rat oral REACH
NOAEL 3500 mg/kg bw/day oral rat oral REACH
NOAEL >=15 other oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL >=1333 mg/kg bw/day oral rat oral REACH

Expert Verdict

Hydrogenated Castor Oil is generally considered safe for use as a skin conditioning, emollient, surfactant, and viscosity control agent.

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Concern Level: Low

Regulatory Flags

eu_children_restricted epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is Hydrogenated Castor Oil Research safe in cosmetics?

Hydrogenated Castor Oil is generally considered safe for use as a skin conditioning, emollient, surfactant, and viscosity control agent. The EU classifies Hydrogenated Castor Oil Research as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.

Is Hydrogenated Castor Oil Research allowed in the EU?

Hydrogenated Castor Oil Research EU regulatory status: permitted. Maximum allowed concentration: 30%. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogenated Castor Oil Research do in cosmetics?

Hydrogenated Castor Oil Research functions as: Surfactant. It is classified as a Surfactant in our database. CAS number: 8001-78-3.

What is the Margin of Safety for Hydrogenated Castor Oil Research?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Hydrogenated Castor Oil Research?

The NOAEL (No Observed Adverse Effect Level) for Hydrogenated Castor Oil Research is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.

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