Hydrogenated Retinol

INCI: HYDROGENATED RETINOL

CAS Number
Not specifically assigned (parent retinol: 68-26-8)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.05%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” retinol and derivatives not specifically restricted under 21 CFR for cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Retinoid family with documented teratogenic potential at high systemic exposure (Repr. 1B H360). EU restriction applies (Annex III pos. 376); mandatory labelling required. Formulator must verify whether hydrogenated retinol converts to retinol equivalents in vivo and calculate total RE contribution.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydrogenated Retinol safe in cosmetics?

Retinoid family with documented teratogenic potential at high systemic exposure (Repr. 1B H360). EU restriction applies (Annex III pos. 376); mandatory labelling required. Formulator must verify whether hydrogenated retinol converts to retinol equivalents in vivo and calculate total RE contribution. The EU classifies Hydrogenated Retinol as "restricted". Safety rating: MODERATE.

Is Hydrogenated Retinol allowed in the EU?

Hydrogenated Retinol EU regulatory status: restricted. Maximum allowed concentration: 0.05%. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrogenated Retinol do in cosmetics?

Hydrogenated Retinol functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (parent retinol: 68-26-8).

What is the Margin of Safety for Hydrogenated Retinol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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