Moderate Cosmetic Ingredient

Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide

INCI: HYDROLYZED CORN/SOY/WHEAT PROTEIN THIOGLYCOLAMIDE/THIOPROPIONAMIDE

CAS Number
Not assigned
Function
Hair conditioning, skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. 8%
🇺🇸 US Status permitted
US Notes Permitted — not specifically restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Wheat protein with MW restriction ≤3500 Da required to prevent type-I hypersensitivity and contact urticaria. Soy allergen may trigger IgE-mediated reactions. Thiol groups reactive with keratin by design but may cause irritation in sensitive individuals. Free thioglycolic acid content must comply with Annex III limits.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide safe in cosmetics?

Wheat protein with MW restriction ≤3500 Da required to prevent type-I hypersensitivity and contact urticaria. Soy allergen may trigger IgE-mediated reactions. Thiol groups reactive with keratin by design but may cause irritation in sensitive individuals. Free thioglycolic acid content must comply with Annex III limits. The EU classifies Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide as "restricted". Safety rating: MODERATE.

Is Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide allowed in the EU?

Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide EU regulatory status: restricted. Maximum allowed concentration: 8%. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide do in cosmetics?

Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide functions as: Hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydrolyzed Corn/Soy/Wheat Protein Thioglycolamide/Thiopropionamide compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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