Hydrolyzed Cottonseed Extract

INCI: HYDROLYZED COTTONSEED EXTRACT

CAS Number
Not specifically assigned (Gossypium spp.)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR; cottonseed products have FDA GRAS status in food

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Gossypol content must be monitored and controlled as gossypol is a polyphenolic aldehyde toxic at systemic levels; refined/hydrolyzed grades should specify gossypol-free status with limited specific toxicology data available for cosmetic safety.

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Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Hydrolyzed Cottonseed Extract safe in cosmetics?

Gossypol content must be monitored and controlled as gossypol is a polyphenolic aldehyde toxic at systemic levels; refined/hydrolyzed grades should specify gossypol-free status with limited specific toxicology data available for cosmetic safety. The EU classifies Hydrolyzed Cottonseed Extract as "permitted". Safety rating: MODERATE.

Is Hydrolyzed Cottonseed Extract allowed in the EU?

Hydrolyzed Cottonseed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Cottonseed Extract do in cosmetics?

Hydrolyzed Cottonseed Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (Gossypium spp.).

What is the Margin of Safety for Hydrolyzed Cottonseed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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