Poor Cosmetic Ingredient

Hydroxyethyl Furanhydroxynaphthoquinone

INCI: HYDROXYETHYL FURANHYDROXYNAPHTHOQUINONE

CAS Number
Not confirmed in standard databases
Function
Likely colorant or skin conditioning; naphthoquinone derivatives are often pigments or bioactives
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status restricted
US Notes If a color additive, requires FDA listing under 21 CFR Parts 73, 74, or 82. Regulatory classification clarity needed.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Naphthoquinone structural alert for skin sensitization, cytotoxicity, and potential genotoxicity. Hydroxynaphthoquinones are restricted in EU (Annex III, henna use only). Furan moiety presents additional genotoxicity concern. Full genotoxicity testing battery (Ames, in vitro micronucleus), HRIPT, and regulatory classification required before use.

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Concern Level: High

Regulatory Flags

potential-allergen colorant

Frequently Asked Questions

Is Hydroxyethyl Furanhydroxynaphthoquinone safe in cosmetics?

Naphthoquinone structural alert for skin sensitization, cytotoxicity, and potential genotoxicity. Hydroxynaphthoquinones are restricted in EU (Annex III, henna use only). Furan moiety presents additional genotoxicity concern. Full genotoxicity testing battery (Ames, in vitro micronucleus), HRIPT, and regulatory classification required before use. The EU classifies Hydroxyethyl Furanhydroxynaphthoquinone as "restricted". Safety rating: POOR.

Is Hydroxyethyl Furanhydroxynaphthoquinone allowed in the EU?

Hydroxyethyl Furanhydroxynaphthoquinone EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxyethyl Furanhydroxynaphthoquinone do in cosmetics?

Hydroxyethyl Furanhydroxynaphthoquinone functions as: Likely colorant or skin conditioning; naphthoquinone derivatives are often pigments or bioactives. It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed in standard databases.

What is the Margin of Safety for Hydroxyethyl Furanhydroxynaphthoquinone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydroxyethyl Furanhydroxynaphthoquinone compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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