2-Methylresorcinol ⭐ (Most extensively assessed)
INCI: 2-METHYLRESORCINOL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for 2-Methylresorcinol ⭐ (Most extensively assessed). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 100 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Expert Verdict
Clastogenic in vitro (chromosome aberrations in V79 cells ± S9) but negative in vivo micronucleus. Severely irritating to rabbit eye when undiluted (ocular corrosion). Acute oral LD50 very low: 390 mg/kg bw in mice. Not for use outside hair dye applications.
Regulatory Flags
Frequently Asked Questions
Is 2-Methylresorcinol ⭐ (Most extensively assessed) safe in cosmetics?
Clastogenic in vitro (chromosome aberrations in V79 cells ± S9) but negative in vivo micronucleus. Severely irritating to rabbit eye when undiluted (ocular corrosion). Acute oral LD50 very low: 390 mg/kg bw in mice. Not for use outside hair dye applications. The EU classifies 2-Methylresorcinol ⭐ (Most extensively assessed) as "prohibited". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is 2-Methylresorcinol ⭐ (Most extensively assessed) allowed in the EU?
2-Methylresorcinol ⭐ (Most extensively assessed) EU regulatory status: prohibited. Maximum allowed concentration: 1.8%. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Methylresorcinol ⭐ (Most extensively assessed) do in cosmetics?
2-Methylresorcinol ⭐ (Most extensively assessed) functions as: Hair dye (oxidative and non-oxidative formulations). It is classified as a cosmetic ingredient in our database. CAS number: 608-25-3.
What is the Margin of Safety for 2-Methylresorcinol ⭐ (Most extensively assessed)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 2-Methylresorcinol ⭐ (Most extensively assessed)?
The NOAEL (No Observed Adverse Effect Level) for 2-Methylresorcinol ⭐ (Most extensively assessed) is 100 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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