Hydroxyethyl-p-Phenylenediamine Sulfate
INCI: HYDROXYETHYL-P-PHENYLENEDIAMINE SULFATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Hydroxyethyl-p-Phenylenediamine Sulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 35 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Prohibited in EU as a coal tar hair dye intermediate; permitted in US with required caution labeling.
Regulatory Flags
Frequently Asked Questions
Is Hydroxyethyl-p-Phenylenediamine Sulfate safe in cosmetics?
Prohibited in EU as a coal tar hair dye intermediate; permitted in US with required caution labeling. The EU classifies Hydroxyethyl-p-Phenylenediamine Sulfate as "prohibited". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is Hydroxyethyl-p-Phenylenediamine Sulfate allowed in the EU?
Hydroxyethyl-p-Phenylenediamine Sulfate EU regulatory status: prohibited. Maximum allowed concentration: 2.0%. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydroxyethyl-p-Phenylenediamine Sulfate do in cosmetics?
Hydroxyethyl-p-Phenylenediamine Sulfate functions as: Oxidative hair dye primary intermediate. It is classified as a cosmetic ingredient in our database. CAS number: 93841-25-9.
What is the Margin of Safety for Hydroxyethyl-p-Phenylenediamine Sulfate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydroxyethyl-p-Phenylenediamine Sulfate?
The NOAEL (No Observed Adverse Effect Level) for Hydroxyethyl-p-Phenylenediamine Sulfate is 35 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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