Hydroxypropyltrimonium Hydrolyzed Silk

INCI: HYDROXYPROPYLTRIMONIUM HYDROLYZED SILK

CAS Number
169590-61-8 [^1_4]
Function
Antistatic, hair conditioning, skin conditioning, humectant
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction; CIR reviewed parent hydrolyzed silk and found it safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Animal-origin ingredient (silkworm Bombyx mori) โ€” may not meet vegan claims; ensure MW of peptide fragments < 3500 Da if claiming read-across to wheat protein CIR limits; no significant toxicological concerns at cosmetic use levels

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Concern Level: Low

Frequently Asked Questions

Is Hydroxypropyltrimonium Hydrolyzed Silk safe in cosmetics?

Animal-origin ingredient (silkworm Bombyx mori) โ€” may not meet vegan claims; ensure MW of peptide fragments < 3500 Da if claiming read-across to wheat protein CIR limits; no significant toxicological concerns at cosmetic use levels The EU classifies Hydroxypropyltrimonium Hydrolyzed Silk as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropyltrimonium Hydrolyzed Silk allowed in the EU?

Hydroxypropyltrimonium Hydrolyzed Silk EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Hydrolyzed Silk do in cosmetics?

Hydroxypropyltrimonium Hydrolyzed Silk functions as: Antistatic, hair conditioning, skin conditioning, humectant. It is classified as a cosmetic ingredient in our database. CAS number: 169590-61-8 [^1_4].

What is the Margin of Safety for Hydroxypropyltrimonium Hydrolyzed Silk?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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