Is Isoamyl Alcohol safe in cosmetics?
Isoamyl Alcohol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Isoamyl Alcohol
INCI: ISOAMYL ALCOHOL
Isoamyl Alcohol (CAS 123-51-3 [^1_10]) is a cosmetic cosmetic ingredient functioning as Solvent, fragrance ingredient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 123-51-3 [^1_10] →
Auto-generated CPSR Part A draft with source citations
Function
Solvent, fragrance ingredient
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no specific 21 CFR restriction for cosmetics; FEMA GRAS for flavoring
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isoamyl Alcohol.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Isoamyl Alcohol.
Regulatory Flags
fragrance-component
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Isoamyl Alcohol by CAS number or substance name.
Studies
2
Lowest NOAEL
23 mg/kg bw/day
Highest NOAEL
431 mg/kg bw/day
COSMOS_DB
Frequently Asked Questions
Is Isoamyl Alcohol allowed in the EU?
Isoamyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isoamyl Alcohol do in cosmetics?
Isoamyl Alcohol functions as: Solvent, fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 123-51-3 [^1_10].
Compliance Tools
Check Isoamyl Alcohol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent
Same category
Fragrance
Acetoin
Excellent
Same category
Skin conditioning, fragrance
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
2,5-DIMETHYLPYRAZINE
Good
Chemical family
Perfuming
2-Ethylhexylal
Good
Chemical family
Solvent
2-Octanol
Good
Chemical family
Fragrance ingredient, solvent
Is Isoamyl Alcohol in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isoamyl Alcohol in your formulation.