Isoamyl Formate

INCI: ISOAMYL FORMATE

CAS Number
110-45-2 [^1_18]
Function
Fragrance / perfuming agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” GRAS flavoring; not prohibited under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Highly volatile fragrance ingredient with negligible absorption; formic acid hydrolysis product may cause irritation at elevated concentrations but not phototoxic.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isoamyl Formate safe in cosmetics?

Highly volatile fragrance ingredient with negligible absorption; formic acid hydrolysis product may cause irritation at elevated concentrations but not phototoxic. The EU classifies Isoamyl Formate as "permitted". Safety rating: GOOD.

Is Isoamyl Formate allowed in the EU?

Isoamyl Formate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoamyl Formate do in cosmetics?

Isoamyl Formate functions as: Fragrance / perfuming agent. It is classified as a cosmetic ingredient in our database. CAS number: 110-45-2 [^1_18].

What is the Margin of Safety for Isoamyl Formate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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