Is Isoamyl Isobutyrate safe in cosmetics?
Isoamyl Isobutyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Isoamyl Isobutyrate
Also known as: Propanoic acid, 2-methyl-, 3-methylbutyl ester, EINECS 218-078-1, FEMA No. 3507, Isoamyl 2-methylpropanoate, Isobutyric acid, isopentyl ester (+5 more)
INCI: ISOAMYL ISOBUTYRATE
Isoamyl Isobutyrate (CAS 2050-01-3) is a cosmetic cosmetic ingredient functioning as Fragrance / flavoring agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 2050-01-3 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance / flavoring agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
3-methylbutyl 2-methylpropanoate
InChIKey
VFTGLSWXJMRZNB-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not prohibited under 21 CFR 700
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isoamyl Isobutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
49
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ISOAMYL ISOBUTYRATE | 1996 | No safety concern at current levels of intake when used as a flavouring agent | TRS 868-JECFA 46/23 | See TRS 868-JECFA 46/68
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Isoamyl Isobutyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Propanoic acid, 2-methyl-, 3-methylbutyl ester
EINECS 218-078-1
FEMA No. 3507
Isoamyl 2-methylpropanoate
Isobutyric acid, isopentyl ester
Isopentyl alcohol, isobutyrate
3-Methyl-1-butyl isobutyrate
3-Methylbutyl 2-methylpropanoate
UNII-RF0ZT103EG
isopentyl 2-methylpropanoate
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
consumer_product
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Europe
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ISOAMYL ISOBUTYRATE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Isoamyl Isobutyrate allowed in the EU?
Isoamyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isoamyl Isobutyrate do in cosmetics?
Isoamyl Isobutyrate functions as: Fragrance / flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 2050-01-3.
Is Isoamyl Isobutyrate used outside cosmetics?
Isoamyl Isobutyrate also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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