Isoborneol

INCI: ISOBORNEOL

CAS Number
124-76-5 [^1_10][^1_11]
Function
Fragrance (perfuming) / denaturant — camphoraceous terpene alcohol
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific restriction under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

NOAEL of 15 mg/kg/day derived from read-across analog (conservative); not genotoxic; RIFM assessment confirms safe under current use conditions.

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isoborneol safe in cosmetics?

NOAEL of 15 mg/kg/day derived from read-across analog (conservative); not genotoxic; RIFM assessment confirms safe under current use conditions. The EU classifies Isoborneol as "permitted". Safety rating: GOOD.

Is Isoborneol allowed in the EU?

Isoborneol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoborneol do in cosmetics?

Isoborneol functions as: Fragrance (perfuming) / denaturant — camphoraceous terpene alcohol. It is classified as a cosmetic ingredient in our database. CAS number: 124-76-5 [^1_10][^1_11].

What is the Margin of Safety for Isoborneol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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