Isobutyl Cinnamate

INCI: ISOBUTYL CINNAMATE

CAS Number
122-67-8 [^1_7]
Function
Fragrance; potential UV-absorbing properties
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FDA lists as food substance (EAFUS); TSCA listed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cinnamate moiety presents structural alert for sensitization; acute oral and dermal LD50 greater than 5 g/kg in animal studies; demonstrates UV absorption capability.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component jecfa_safe

Frequently Asked Questions

Is Isobutyl Cinnamate safe in cosmetics?

Cinnamate moiety presents structural alert for sensitization; acute oral and dermal LD50 greater than 5 g/kg in animal studies; demonstrates UV absorption capability. The EU classifies Isobutyl Cinnamate as "permitted". Safety rating: MODERATE.

Is Isobutyl Cinnamate allowed in the EU?

Isobutyl Cinnamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Cinnamate do in cosmetics?

Isobutyl Cinnamate functions as: Fragrance; potential UV-absorbing properties. It is classified as a cosmetic ingredient in our database. CAS number: 122-67-8 [^1_7].

What is the Margin of Safety for Isobutyl Cinnamate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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