Isobutyl Formate

INCI: ISOBUTYL FORMATE

CAS Number
542-55-2 [^1_11]
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Highly volatile and flammable fragrance ingredient; Cramer Class I with inhalation exposure well below TTC threshold; not a PBT substance.

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Concern Level: Low

Regulatory Flags

fragrance-component jecfa_safe

Frequently Asked Questions

Is Isobutyl Formate safe in cosmetics?

Highly volatile and flammable fragrance ingredient; Cramer Class I with inhalation exposure well below TTC threshold; not a PBT substance. The EU classifies Isobutyl Formate as "permitted". Safety rating: GOOD.

Is Isobutyl Formate allowed in the EU?

Isobutyl Formate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Formate do in cosmetics?

Isobutyl Formate functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 542-55-2 [^1_11].

What is the Margin of Safety for Isobutyl Formate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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