Delta-Valerolactone

INCI: DELTA-VALEROLACTONE

CAS Number
542-28-9
Function
Solvent and chemical intermediate
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited toxicological data available for cosmetic use; primarily used as an industrial solvent and reagent with no RIFM or CIR safety assessment; cosmetic product safety report should include dermal penetration data to justify use.

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Concern Level: Moderate

Frequently Asked Questions

Is Delta-Valerolactone safe in cosmetics?

Limited toxicological data available for cosmetic use; primarily used as an industrial solvent and reagent with no RIFM or CIR safety assessment; cosmetic product safety report should include dermal penetration data to justify use. The EU classifies Delta-Valerolactone as "permitted". Safety rating: MODERATE.

Is Delta-Valerolactone allowed in the EU?

Delta-Valerolactone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Delta-Valerolactone do in cosmetics?

Delta-Valerolactone functions as: Solvent and chemical intermediate. It is classified as a cosmetic ingredient in our database. CAS number: 542-28-9.

What is the Margin of Safety for Delta-Valerolactone?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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