Isodon Inflexus Branch/Leaf Extract

INCI: ISODON INFLEXUS BRANCH/LEAF EXTRACT

CAS Number
Not assigned
Function
Bleaching (skin lightening) agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction; general cosmetic safety under 21 CFR 740.10 applies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CAS number assigned; no CIR, SCCS, or RIFM review; no NOAEL/LOAEL data; botanical from Lamiaceae family with potential for phytochemical-related sensitization; skin-lightening claim requires demonstration of safety at intended use level.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen natural-origin

Frequently Asked Questions

Is Isodon Inflexus Branch/Leaf Extract safe in cosmetics?

No CAS number assigned; no CIR, SCCS, or RIFM review; no NOAEL/LOAEL data; botanical from Lamiaceae family with potential for phytochemical-related sensitization; skin-lightening claim requires demonstration of safety at intended use level. The EU classifies Isodon Inflexus Branch/Leaf Extract as "permitted". Safety rating: POOR.

Is Isodon Inflexus Branch/Leaf Extract allowed in the EU?

Isodon Inflexus Branch/Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isodon Inflexus Branch/Leaf Extract do in cosmetics?

Isodon Inflexus Branch/Leaf Extract functions as: Bleaching (skin lightening) agent. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Isodon Inflexus Branch/Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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