Is Isoeugenyl Phenylacetate safe in cosmetics?
Isoeugenyl Phenylacetate has a safety rating of "GOOD" in our database. EU status: prohibited. US status: permitted.
Good
Cosmetic Ingredient
Isoeugenyl Phenylacetate
Also known as: Benzeneacetic acid, 2-methoxy-4-(1-propenyl)phenyl ester, Benzeneacetic acid, 2-methoxy-4-(1-propen-1-yl)phenyl ester, Acetic acid, phenyl-, 2-methoxy-4-propenylphenyl ester, EINECS 204-381-6, FEMA No. 2477 (+6 more)
INCI: ISOEUGENYL PHENYLACETATE
Isoeugenyl Phenylacetate (CAS 120-24-1) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 120-24-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Isoeugenyl Phenylacetate is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H351).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance (perfuming)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2-methoxy-4-prop-1-enylphenyl) 2-phenylacetate
InChIKey
YYLCMLYMJHKLEJ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Permitted — no specific CFR restriction; RIFM Expert Panel concluded safe as described (2024)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isoeugenyl Phenylacetate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
1263
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
ISOEUGENYL PHENYLACETATE | 2003 | No safety concern at current levels of intake when used as a flavouring agent | TRS 922-JECFA 61/96 | FAS 52-JECFA 61/389
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Isoeugenyl Phenylacetate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
Benzeneacetic acid, 2-methoxy-4-(1-propenyl)phenyl ester
Benzeneacetic acid, 2-methoxy-4-(1-propen-1-yl)phenyl ester
Acetic acid, phenyl-, 2-methoxy-4-propenylphenyl ester
EINECS 204-381-6
FEMA No. 2477
Isoeugenyl alpha-toluate
2-Methoxy-4-(1-propenyl)phenyl benzeneacetate
2-Methoxy-4-propenylphenyl phenylacetate
2-Methoxy-4-(1-propen-1-yl)phenyl phenylacetate
4-Propenylguaiacyl phenylacetate
UNII-8VQ5B1Y5ZC
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isoeugenyl Phenylacetate allowed in the EU?
Isoeugenyl Phenylacetate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Isoeugenyl Phenylacetate do in cosmetics?
Isoeugenyl Phenylacetate functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 120-24-1.
Is Isoeugenyl Phenylacetate used outside cosmetics?
Isoeugenyl Phenylacetate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Isoeugenyl Phenylacetate have different safety status in cosmetics vs industrial chemicals?
Isoeugenyl Phenylacetate is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H351).
Compliance Tools
Check Isoeugenyl Phenylacetate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Chemical family
fragrance; solvent; anti-parasitic
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Chemical family
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