Ketotravoprost

INCI: KETOTRAVOPROST

CAS Number
404830-45-1
Function
Hair conditioning, eyelash growth promotion via prostaglandin analogue mechanism
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status prohibited
US Notes Not explicitly prohibited under 21 CFR, but parent compound Travoprost is an FDA-approved prescription drug for ophthalmic use; cosmetic application raises drug-cosmetic boundary concerns

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potent pharmacological activity with documented adverse effects including iris and periorbital hyperpigmentation, periorbital fat atrophy, eye inflammation, and hypertrichosis; contraindicated in pregnancy; Sweden has banned prostaglandin analogue eyelash serums and regulatory bodies including SCCS and UK OPSS have flagged serious consumer safety risks.

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Concern Level: High

Frequently Asked Questions

Is Ketotravoprost safe in cosmetics?

Potent pharmacological activity with documented adverse effects including iris and periorbital hyperpigmentation, periorbital fat atrophy, eye inflammation, and hypertrichosis; contraindicated in pregnancy; Sweden has banned prostaglandin analogue eyelash serums and regulatory bodies including SCCS and UK OPSS have flagged serious consumer safety risks. The EU classifies Ketotravoprost as "prohibited". Safety rating: POOR.

Is Ketotravoprost allowed in the EU?

Ketotravoprost EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Ketotravoprost do in cosmetics?

Ketotravoprost functions as: Hair conditioning, eyelash growth promotion via prostaglandin analogue mechanism. It is classified as a cosmetic ingredient in our database. CAS number: 404830-45-1.

What is the Margin of Safety for Ketotravoprost?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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