Larixol

INCI: LARIXOL

CAS Number
1438-66-0
Function
Skin conditioning; investigated for skin-lightening activity
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Defined single molecule requiring rigorous toxicological profiling; antimicrobial and anti-inflammatory activity documented but potential phototoxicity not assessed; use in skin-lightening compositions warrants dose-finding safety study.

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Concern Level: Moderate

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Larixol safe in cosmetics?

Defined single molecule requiring rigorous toxicological profiling; antimicrobial and anti-inflammatory activity documented but potential phototoxicity not assessed; use in skin-lightening compositions warrants dose-finding safety study. The EU classifies Larixol as "permitted". Safety rating: MODERATE.

Is Larixol allowed in the EU?

Larixol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Larixol do in cosmetics?

Larixol functions as: Skin conditioning; investigated for skin-lightening activity. It is classified as a cosmetic ingredient in our database. CAS number: 1438-66-0.

What is the Margin of Safety for Larixol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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