Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Laureth-23. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=150 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 750 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=150 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=2000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
CIR concluded safe in present practices. Non-irritating, non-sensitizing. Critical control: 1,4-dioxane and residual ethylene oxide.
Regulatory Flags
Frequently Asked Questions
Is Laureth-23 safe in cosmetics?
CIR concluded safe in present practices. Non-irritating, non-sensitizing. Critical control: 1,4-dioxane and residual ethylene oxide. The EU classifies Laureth-23 as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Laureth-23 allowed in the EU?
Laureth-23 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Laureth-23 do in cosmetics?
Laureth-23 functions as: Surfactant, Emulsifying, Cleansing, Solubilizer. It is classified as a Surfactant in our database. CAS number: 68439-50-9.
What is the Margin of Safety for Laureth-23?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Laureth-23?
The NOAEL (No Observed Adverse Effect Level) for Laureth-23 is >=500 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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